Can the cannabis compounds CBDA and CBGA prevent COVID infection and prevent the coronavirus from mutating?
Smoking cannabis will maybe not prevent you from getting infected by covid, but 2 cannabis compounds (CBDA and CBGA) have probably the potential to prevent getting infected and spreading the coronavirus.
You will not feel high lol ๐
CBDA and CBGA could prevent SARS-CoV-2 from infecting human cells.
CBDA (Cannabidiolic acid) and Cannabigerolic acid (CBGA) are cannabinoids found in cannabis plants.
It is most abundant in the glandular trichomes on the female seedless flowers or more accurately infructescence often colloquially referred to as buds.
CBDA is the chemical precursor to cannabidiol (CBD).
CBGA is the acidic form of cannabigerol (CBG).
Our study suggests two compounds found in commonly found in hemp — cannabigerolic acid (CBGA) and cannabidiolic acid (CBDA) — prevent coronavirus from entering cells that typically line internal organs and skin in a lab setting.
In the study, these acids were able to bind to the SARS-CoV-2 spike protein — the same target used in COVID-19 vaccines and antibody therapy.
Once bound, this step could block a critical step in the pathogen process used to infect the cell.
โThat means cell entry inhibitors, like the acids from hemp, could be used to prevent SARS-CoV-2 infection and also to shorten infections by preventing virus particles from infecting human cells.
They bind to the spike proteins so those proteins canโt bind to the ACE2 enzyme, which is abundant on the outer membrane of endothelial cells in the lungs and other organs,โ
Both cannabis compounds were found equally effective against the SARS-CoV-2 alpha and beta variants.
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